The TRG, founded in 2001 is organized as an independent, nonprofit organization of scientific investigators who conduct research at the institutions with which they are affiliated. The TRG aims to advance knowledge about the cause, pathogenesis and clinical impact of tremor disorders and to develop and implement scientific strategies to examine promising therapeutic interventions. The views of the TRG do not necessarily represent the views of the institutions with which the investigators are affiliated.


The Tremor Research Group (TRG) representing a consortium of scientific investigators from centers who are committed to cooperative planning, implementation, analysis and reporting of controlled clinical trials and of other research for tremor disorders. Membership is by invitation only and includes researchers who have distinguished themselves in the field of tremor.


The TRG is governed primarily by a three member Executive Committee consisting of a President, Vice President, and Secretary/Treasurer who are elected by the voting members.The Executive Committee members hold terms of three years and may be elected to succeed themselves for up to two consecutive terms. New members are nominated by current membership and approved by 2/3 of entire membership.


The TRG has developed, validated, and published a comprehensive rating scale for essential tremor (TETRAS). Education and credentialing for the scale is available.  The TRG is serving was the core rating site for the focused ultrasound for essential tremor study (ET002), sponsored by InSightec. The TRG and TRG sites have worked with multiple pharmaceutical companies including Sage, Biohaven, CAVION and CADENT to develop and implement clinical trials for essential tremor.


  • Lyons KE, Pahwa R, Comella CL, Eisa MS, Elble RJ, Fahn S, Jankovic J, Juncos JL, Koller WC, Ondo WG, Sethi KD, Stern MB, Tanner CM, Tintner R, Watts RL. Benefits and risks of pharmacological treatments for essential tremor. Drug Saf 2003;26:461-81.
  • Elble RJ for the Tremor Research Group and Conference Attendees. Report from a U.S. conference on essential tremor. Mov Disord 2006;21:2052-2061.
  • Elble RJ, Pullman SL, Matsumoto JY, Raethjen J, Deuschl G, Tintner R and the Tremor Research Group. Tremor amplitude is logarithmically related to 4- and 5-point tremor rating scales. Brain 2006;129:2660-2666.
  • Elble R, Comella C, Fahn S, Hallett M, Jankovic J, Juncos JL, LeWitt P, Lyons K, Ondo W, Pahwa R, Sethi K, Stover N, Tarsy D, Testa C, Tintner R, Watts R, Zesiewicz T. Reliability of a new scale for essential tremor. Mov Disord 2012;27:1567-1569.
  • Elble RJ. The Essential Tremor Rating Assessment Scale. J Neurol Neuromed (2016) 1(4): 34-38
  • Ondo W, Hashem V, Lewitt P, Pahwa R, Tarsy D, Shih L, Zesiewicz T, Elble R. Comparison of the Fahn-Tolosa-Marin Clinical Rating Scale and The Essential Tremor Rating Assessment Scale (TETRAS). Mov Disord Clin Practice. DOI: 10.1002/mdc3.12560
  • Ondo W, Lewitt P, Elias J. Incisionless Thalamotomy for Essential Tremor by MR-guided Focused Ultrasound – Randomized, Sham-controlled Trial (abstract) MDS 2014.
  • Elble R, Bhargava P, Dhaka L, Jalan P, Kaul S, Pandav V, Lyons K, Ondo W, Pahwa R, Sethi K, Tarsy D, Tintner R. Reliability of the Essential Tremor Rating Assessment Scale in untrained neurology residents (abstract) AAN 2013
  • Yeo C, Ondo W, Kuo S for the Tremor Research Group. Tremor Research Group Essential Tremor Rating Scale (TETRAS):
    Assessing Impact of Different Item Instructions. (abstract) AAN 2018